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ADVANCED SOLID TUMORS: PHASE 1: LAST LINE: SLITRK6 ADC

Title
Genmab GCT1106-01 Phase 1
Study Title
Site Link
Malignancy
Bone, Breast, Bladder, Colon, Prostate, Melanoma, RCC, Kidney, Rectal, Lung, NSCLC, SCLC, Soft Tissue, Ovarian, Endometrial, Cervical
Stage
Disease Setting
Metastatic/Palliative
Line Of Therapy
Last Line
Investigational Agent
GEN1106
Drug Class
SLITRK6 ADC
PI
Dan Vaena, MD
Sponsor
Genmab
Phase
Status
Key Eligibility Criteria
Key Eligibility Criteria Details
  • Have received and progressed on, been ontolerant to, or be inelgibile for all available SOC therapies known to provide a survival or QOL benefit for the specific tumor type
  • Measurable disease
  • ECOG PS 0-1
  • No prior treatment with topo-1 inhibitor based ADC
Objective
  • Primary
    • DLT
    • Safety
  • Secondary
    • ORR
    • PK
    • DCR
    • DOR
    • TTR
Assessment Frequency
_
Assessment Frequency 2
_



Assessment Frequency Link
Path
Any
Dosing Frequency
Control Agents
Study Protocol
Randomized
No
X