Translating Cancer Into Cure.
Often described as “from bench to bedside” research, translational drug discovery and development is based on the concept that the creation of new drugs should relate directly to patient needs and should couple laboratory research with observations made in the clinic. Translational Research targets specific mechanisms underlying clinically relevant problems and designs drugs to address those issues directly.
By understanding the specific mutations, scientists can develop more specific, precise therapy that is highly individualized based on the mutation. Targeted therapy is becoming the more prevalent approach in cancer therapeutics, and requires the collaboration of a team of investigators to:
- Identify new molecular targets
- Validate these targets in cell cultures and then animal models
- Develop new drugs to address these targets
- Test new drugs in clinical trials